An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
نویسندگان
چکیده
منابع مشابه
An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
The number of significant genetic associations with common complex traits is constantly increasing. However, most of these associations have not been understood at molecular level. One of the mechanisms mediating the effect of DNA variants on phenotypes is gene expression, which has been shown to be particularly relevant for complex traits. This method tests in a cellular context the effect of ...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2010
ISSN: 1940-087X
DOI: 10.3791/2279